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Paper · arXiv

Artificial intelligence and biosecurity: capabilities, threat pathways, and defense-in-depth governance

Artificial intelligence is reshaping biological research across an increasingly connected digital-to-physical workflow. General-purpose large language models can retrieve and integrate scientific information, support experimental planning, and computational analysis; biological foundation models can predict, optimize, and generate proteins, genes, and genome-scale sequences; agentic systems can coordinate multistep research tasks; automated laboratories can partially close the design-build-test-learn cycle. These technologies could greatly benefit medicine, public health, and biotechnology. However, their biosecurity risk depends not only on what the AI can do, but also on who uses it, th...

AuthorsCandace S. Y. Chan, Aris Karatzikos, Ilias Georgakopoulos-Soares
Primary categorycs.AI
Published14 September 2026
Last updated at source14 September 2026
cs.AI
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