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Paper · arXiv

ClinAgent: A ReAct-Based Agent for Conversational Access to Clinical Trial Information

Querying clinical trial registries remains a manual and error-prone process, requiring researchers to navigate large volumes of semi-structured data without support for natural language interaction or cross-source synthesis. To address this, we introduce ClinAgent, a conversational system based on agentic Retrieval-Augmented Generation (RAG) that enables clinicians and researchers to query clinical trial information in plain language and receive grounded, up-to-date responses across multi-turn interactions. The system centers on a Large Language Model (LLM) agent following the ReAct paradigm, which iteratively reasons over queries, selects among a set of integrated tools, and refines its ...

AuthorsAntonino Vaccarella, Riccardo Cantini, Domenico Talia et al.
Primary categorycs.AI
Published12 September 2026
Last updated at source12 September 2026
cs.AIcs.CLcs.IR
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