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Paper · arXiv

Learning to Adapt and Calibrate: Score Distribution Alignment for Few-Shot Uncertainty Prediction in Medical VLMs

Uncertainty estimation for medical vision--language models (VLMs) using conformal prediction has gained increasing attention due to its distribution-free coverage guarantees. However, standard conformal prediction relies on exchangeability between calibration and test data and typically requires a sufficiently large calibration set to obtain reliable coverage. These assumptions are difficult to satisfy in few-shot transfer settings, where only a small labeled support set is available to adapt a pretrained VLM to a new medical task, while an unlabeled query set is used for evaluation. Supervised fine-tuning on the support set changes the model parameters and consequently shifts the nonconf...

AuthorsXuan Cuong Ngo, Ngan Le
Primary categorycs.CV
Published9 September 2026
Last updated at source9 September 2026
cs.CV
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