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Paper · arXiv

TabBench-Bio: A Living Benchmark for Machine Learning on High-Dimensional Biomedical Tables

Biomedical tables often combine thousands of measured variables with only tens or hundreds of labelled samples, a regime that is poorly represented in general-purpose tabular benchmarks. We introduce TabBench-Bio, a living and interactive benchmark of 43 biomedical datasets spanning multiple domains. Under a shared cross-validation protocol, we compare classical estimators, neural networks, and tabular foundation models across 28 feature-by-sample operating points. At the reference cell of 10,000 features and 100 training samples, RealTabPFN 2.5 has the highest point estimate, closely followed by TabPFN 3 and Logistic Regression. A paired bootstrap over the target pool separates RealTabPF...

AuthorsJules Kreuer, Sofiane Ouaari, Julia Hellmig et al.
Primary categorycs.LG
Published7 September 2026
Last updated at source26 September 2026
cs.LGcs.AI
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