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Paper · arXiv

Interpretable Symptom Vectors for Depression in a Large Language Model

Patients with depression present with diverse symptom profiles, yet clinical practice routinely reduces this variation to a single severity score. Large language models (LLMs) can potentially capture various symptoms and their severity from patient speech. However, how depressive symptoms are represented inside LLMs remains poorly understood, limiting clinical trust. To examine whether internal model activations match clinician judgment, we analyzed the residual stream of Gemma-3-27B-PT using mechanistic interpretability techniques. Recording activations across symptom descriptions drawn from validated clinical instruments, we found that symptom groups geometrically separated the most at ...

AuthorsFangyi Zhu, Ajay Subramanian, Allison Constant et al.
Primary categorycs.CL
Published1 September 2026
Last updated at source1 September 2026
cs.CLcs.AIcs.LGq-bio.NC
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