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Paper · arXiv

Semi-Supervised Virtual Staining via Morphology Preservation and Histopathological Realism Constraints

Virtual staining aims to computationally generate target-stained histopathological images while reducing the cost and time associated with conventional staining procedures. However, existing methods rely predominantly on strictly paired and accurately registered training data, which are difficult and expensive to obtain in routine practice. To reduce this dependence, we propose a stable semi-supervised virtual staining framework that jointly exploits both limited paired data and abundant unpaired source images. Directly incorporating unpaired images is challenging because their generated results lack corresponding targets for supervision, potentially leading to unrealistic staining, morph...

AuthorsBaoshun Wang, Weiping Lin, Linwu Wang et al.
Primary categorycs.CV
Published1 September 2026
Last updated at source1 September 2026
cs.CVcs.AI
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