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Paper · arXiv

SlideMix: Enhancing Whole Slide Image Analysis via Multimodal Shuffling

Histopathological whole slide images (WSIs) are central to cancer diagnosis, but their gigapixel scale, tissue heterogeneity, weak slide-level supervision, sparse diagnostic regions, and multi-scale evidence make robust automated analysis challenging. Multiple instance learning (MIL) is widely used to aggregate tile-level features into slide-level predictions, yet existing augmentation strategies often perturb tissue regions without preserving diagnostic relevance, slide context, or cross-scale structure. We propose SlideMix, a model-agnostic multimodal augmentation framework for MIL-based WSI analysis. SlideMix uses a retrieval-augmented vision-language model (VLM)-based Visual-Language ...

AuthorsChad Wong, Sicheng Chen, Tianyi Zhang et al.
Primary categorycs.CV
Published31 August 2026
Last updated at source31 August 2026
cs.CV
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