Generating Clinical Vignettes that Preserve Cognitive Formulations
Large language models can generate fluent clinical case vignettes, but fluency alone does not ensure fidelity to a specifiable clinical structure. We introduce FORMA, a theory-grounded framework that compiles a cognitive model of a disorder into a directed weighted graph, samples a person-specific configuration of that graph, and validates whether the generated vignette preserves the specified components and causal links. We instantiate FORMA on Posttraumatic Stress Disorder using the Ehlers and Clark cognitive model, generating 16,500 vignettes across 500 personas, 11 generation models, and three ablation conditions. Evaluation combines an external edge-recovery probe, two clinical exper...
| Authors | Amit Oren, Nimrod Hertz-Palmor, Dean Ariel et al. |
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| Primary category | cs.CL |
| Published | 30 August 2026 |
| Last updated at source | 30 August 2026 |
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