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Paper · arXiv

Structured Evidence Routing for Incident Risk Prediction from Multimodal Longitudinal EHRs

Incident risk prediction from longitudinal electronic health records (EHRs) is challenging because relevant signals are multimodal, weak in isolation, and distributed across irregular patient histories. We propose structured evidence routing, a router-predictor-reviewer workflow that separates full-record access from disease-specific assessment. The router organizes the complete pre-index EHR into a compact summary and targeted evidence slices; the predictor uses this evidence to form an evidence-linked risk assessment, which the reviewer critiques. For comparison with supervised EHRSHOT baselines, we pair the routed evidence summaries with a supervised classifier readout. Across five 1-y...

AuthorsAnimesh Agarwal, Meysam Ghaffari, Nina Fatehi et al.
Primary categorycs.AI
Published24 August 2026
Last updated at source24 August 2026
cs.AI
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