Anatomy-Informed Neural Networks: Encoding Anatomic Priors in Loss and Architecture, with an SE(3) Formulation of Guidewire-Induced Aortoiliac Deformation
Deep-learning models of anatomy can be numerically plausible yet anatomically impossible, and they generalize poorly when data are scarce. We introduce Anatomy-Informed Neural Networks (AINN), in which soft anatomic priors enter as penalty terms in the loss (e.g., a branching penalty that treats a renal transplant artery off the iliac instead of the aorta as unexpected rather than impossible), in direct analogy to a physics-informed neural network, and hard anatomic priors (e.g., continuity of the vessel) are built into the architecture and state representation, making such invalid predictions impossible by construction wherever the prior admits architectural enforcement. We develop it on...
| Authors | David P. Stonko |
|---|---|
| Primary category | cs.AI |
| Published | 21 August 2026 |
| Last updated at source | 21 August 2026 |
Silytics shows public metadata from arXiv and links to the original. Information may be incomplete or out of date. Last refreshed 17 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.