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Paper · arXiv

Graph-Based Approaches to Learning Epileptogenic Zone Localization Using Stereo-EEG Recordings

The epileptogenic zone (EZ) is the brain region that generates seizures in an individual, and is the target of epilepsy surgery. Localizing the EZ from stereo-EEG (sEEG) recordings supports surgical planning, but manual interpretation is time-consuming and focuses on seizure recordings. Graphical learning models of resting-state functional connectivity among the recorded brain regions are an attractive alternative, but depend crucially on the network topology chosen for the model. We present a controlled study of graph-based models to explore how graph topology affects EZ localization from resting-state sEEG in 40 patients. Using the same simple learnable model and leave-one-patient-out e...

AuthorsDaniel Wendelken, Brian Ervin, Ravindra Arya et al.
Primary categorycs.LG
Published19 August 2026
Last updated at source19 August 2026
cs.LG
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