Anatomical and Physical Supervision for CT-less PET Attenuation Correction: BIC-MAC 2026 Challenge
This report describes our submission to the Big Cross-Modal Attenuation Correction (BIC-MAC) 2026 Challenge for CT-less PET attenuation correction through multimodal pseudo-CT synthesis. We build upon a standard nnU-Net architecture and combine anatomical and physical supervision to improve both pseudo-CT quality and downstream PET reconstruction. Anatomical supervision is introduced through a frozen TotalSegmentator feature extractor, anatomy-guided structural constraints and patch sampling, while physical supervision is achieved using a differentiable attenuation correction factor projection loss based on multi-angle attenuation projections. Furthermore, the network is initialized with ...
| Authors | Petros Chatzitoulousis, George K. Matsopoulos |
|---|---|
| Primary category | cs.CV |
| Published | 16 August 2026 |
| Last updated at source | 16 August 2026 |
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