In Defense of OCTA: The Reconstruction-Utility Gap in OCT-to-OCTA Synthesis
Optical coherence tomography angiography (OCTA) images retinal blood flow, giving capillary-perfusion and foveal-avascular-zone biomarkers that grade diabetic-retinopathy ischemia. Because OCTA hardware is less common than structural OCT, recent work synthesizes it from OCT, reporting strong reconstruction (3D PSNR > 31 dB, SSIM > 0.9). We ask not whether the synthetic image looks similar, but whether it supports the measurements OCTA is acquired for. A frozen real-OCTA segmenter, applied as a probe to two synthesizers (XOCT, TransPro), shows downstream Dice falling with structural fineness: large vessels survive (0.862 -> 0.831) while the fine capillary network collapses (0.798 -> 0.635,...
| Authors | Michael Chertok, Alon Tiosano, Orly Gal-Or et al. |
|---|---|
| Primary category | cs.LG |
| Published | 16 August 2026 |
| Last updated at source | 16 August 2026 |
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