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Paper · arXiv

Uncertainty Identifies Difficult Samples Across Methods: A Multi-Task Study on a Heterogeneous Skin Lesion Dataset

Skin lesion classifiers can be confidently wrong on the cases that matter most, so knowing when a prediction should not be trusted is clinically as useful as the prediction. We study uncertainty quantification on a dataset pooled from many ISIC sources, with a shared backbone and two jointly learned heads: a binary malignant versus non-malignant head and a five-class diagnostic head. Five UQ methods (MC Dropout, DropConnect, Flipout, Deep Ensembles, DUQ) are compared on accuracy, calibration, uncertainty decomposition, and risk-coverage. Difficulty is largely method-agnostic: even methods with narrow entropy distributions rank the same samples as hard (per-sample entropy correlations of $...

AuthorsLeon Koole, Jiapan Guo, Matias Valdenegro-Toro
Primary categorycs.CV
Published14 August 2026
Last updated at source14 August 2026
cs.CVcs.LG
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