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Paper · arXiv

HIPNO: Symmetry-Aware Physics-Informed Neural Operators for Noninvasive Hemodynamic Inference

Continuous hemodynamic monitoring guides treatment decisions in surgery and intensive care. However, gold-standard signals are only measured in severe cases due to risks associated with invasive measurement. In this work, we introduce HIPNO (Hemodynamic Inference via Physics-informed Neural Operators) to recover hemodynamic state from ubiquitous, non-invasive signals and expand access to advanced monitoring. HIPNO addresses a problem of scale symmetry in physics-informed hemodynamic inference, where different combinations of flow, resistance, and compliance can generate the same observed pressure. We identify the symmetry group of the observation model and parameterize the network in its ...

AuthorsYunbei Pan, Jiahang Sha, Simon A. Lee et al.
Primary categoryq-bio.QM
Published8 August 2026
Last updated at source8 August 2026
q-bio.QMcs.LGeess.SP
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