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Paper · arXiv

Protecting patient privacy in clinical foundation models: Technical and legal perspectives

Clinical foundation models trained on large-scale patient data are increasingly used for decision support, screening, and public health planning. As deployment expands, privacy risk arises from model-mediated leakage, yet its prevalence and severity remain poorly quantified. Models can disclose sensitive training artifacts, enabling patient re-identification in ways not captured by data-handling controls alone. As a result, existing frameworks, including HIPAA and GDPR, offer limited protection against assessing and addressing. We propose a practical framework for assessing privacy risk in clinical foundation models, illustrate realistic leakage scenarios across deployment settings, map t...

AuthorsSana Tonekaboni, Lena Stempfle, Sasha Ronaghi et al.
Primary categorycs.AI
Published7 August 2026
Last updated at source15 September 2026
cs.AIcs.LG
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