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Paper · arXiv

bioMoR: Biology-Guided Mixture-of-Recursions for Effective Genomic Learning

Transformer models for high-dimensional omics analysis process thousands of genes or pathways, although only a subset requires deep computation. Mixture-of-Recursions (MoR) improves efficiency through adaptive token-choice or expert-choice routing. We propose bioMoR, which, to the best of our knowledge, is the first framework to apply MoR to gene-level and pathway-level learning. Our contributions include identifying three locations for integrating structured biological knowledge within an MoR backbone: graph-based information sharing refines token embeddings, a structural bias guides self-attention toward biologically related tokens, and a graph-aware router uses neighborhood information...

AuthorsKoushik Howlader, Tirtho Roy, Md Tauhidul Islam et al.
Primary categorycs.AI
Published7 August 2026
Last updated at source10 August 2026
cs.AIcs.LG
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