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Paper · arXiv

Tracing the Heart: An Evidence-Linked Pipeline for Heart-Failure Feature Engineering

Electronic health record (EHR) feature engineering is a major bottleneck in clinical research and AI, accounting for 39-45% of data scientists' workload. This is especially pronounced in heart failure, which affects an estimated 6.7 million U.S. adults and requires integrating fragmented EHR data with disease-specific, guideline-based clinical reasoning. Existing rule-based and large language model (LLM)-based approaches offer only partial automation with limited maintainability and evidence traceability. We developed the Nimblemind Multi-Agent System (nMAS), an evidence-linked, rubric-grounded pipeline for automated heart-failure feature engineering, and evaluated it on 500 dummy patient...

AuthorsSoorya Ram Shimgekar, Michelle Hu, Dorisa Shehi et al.
Primary categorycs.AI
Published6 August 2026
Last updated at source6 August 2026
cs.AIcs.LG
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