When Measurement Conventions Masquerade as Calibration Gains in Cardiac Digital Twins
Cardiac digital twins convert clinical images into physiological measurements through observation operators, yet calibration studies often assume a fixed reference convention. Across four shared-backbone echocardiographic EF front-ends, phase conditioning appears to remove CAMUS baseline bias. Matched-reference analysis rejects this gain: singleplane ground-truth EF error is statistically indistinguishable across models, while single-plane ground-truth EF exceeds CAMUS biplane clinical EF by +6.30 points, explaining nearly all baseline bias. A prespecified EchoNet-Dynamic replication, with released data and our extractor aligned to the apical four-chamber plane, removes baseline overestim...
| Authors | Dang P. M. Cao, Hieu Pham |
|---|---|
| Primary category | cs.CV |
| Published | 3 August 2026 |
| Last updated at source | 1 September 2026 |
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