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Paper · arXiv

ProgFormer: Hierarchical Voxel Diffusion Transformer for Longitudinal Brain MRI Prediction

Predicting future structural MRI of a brain is challenging because longitudinal changes are often subtle and confined to specific anatomical regions, while most subject-specific brain structure remains stable over time. An effective model should therefore preserve global brain structural consistency while remaining sensitive to fine-grained disease progression. Existing latent-space-based methods improve computational efficiency, but suffer from information loss during their compression-reconstruction procedure. In contrast, direct voxel-space methods avoid latent reconstruction but commonly use a unified prediction pathway to model brain structure and progression-related changes. Subtle ...

AuthorsDexuan Ding, Yuankai Qi, Luping Zhou et al.
Primary categorycs.CV
Published30 July 2026
Last updated at source30 July 2026
cs.CV
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