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Paper · arXiv

Aletheia: An Offline-First Clinical Decision Support System for Differential Diagnosis in Low-Resource Healthcare Settings

Access to specialist clinical expertise remains severely limited across sub-Saharan Africa, where physician-to-patient ratios can fall below 1:25,000 in rural settings. Existing AI-assisted diagnostic tools predominantly require reliable internet connectivity and high-specification hardware, rendering them impractical for frontline healthcare workers in district hospitals and health centres. This paper presents Aletheia, an offline-first clinical decision support system designed for low-resource healthcare contexts across sub-Saharan Africa. Aletheia is built upon Qwen2.5-3B-Instruct, fine-tuned using Quantised Low-Rank Adaptation (QLoRA) on a curated dataset of 27,000 clinical reasoning ...

AuthorsJoseph Walusimbi, Ann Move Oguti, Abubakhari Sserwadda et al.
Primary categorycs.AI
Published14 July 2026
Last updated at source4 September 2026
cs.AIcs.LGq-bio.OT
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