Disentangling Acoustic Cues in Alzheimer's Pathology and Perception: The Roles of Language and Gender
Acoustic biomarkers show promise for detecting Alzheimer's Disease (AD), yet whether the cues driving diagnostic AI align with those salient to human listeners is underexplored across languages and genders, where pathological markers and perceptual strategies differ. We train models to predict clinical AD status (pathology) and human perceptual scores across Mandarin and Greek, male and female speakers. Using SHAP for interpretability and statistical models for validation, we compare feature importance by subgroup. Results reveal a context-dependent divergence: pathological-perceptual alignment is significant for Mandarin and female speakers but disappears for Greek and male speakers, whe...
| Authors | Liu He, Yuanchao Li, Yin-Long Liu et al. |
|---|---|
| Primary category | cs.SD |
| Published | 27 July 2026 |
| Last updated at source | 27 July 2026 |
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