Plato-Bio: verification-first biological novelty screening with temporal rediscovery and structural benchmarks
Large language model research agents can connect literature retrieval, analysis code, and manuscript preparation, but coherent output does not establish scientific validity. We developed Plato-Bio, a biology-routed extension of the open Plato/Denario architecture that couples explicit workflow states with provenance records, citation checks, claim-to-evidence links, scoped file writes, and publication gates. A source audit identified and repaired three defects that could distort evaluation: loss of task domain in the default factory, omission of declared method signals from scoring, and evidence sidecars that lacked the drafted-claim denominator. On the current clean revision, the full Py...
| Authors | Stefan G. Creadore |
|---|---|
| Primary category | cs.AI |
| Published | 27 July 2026 |
| Last updated at source | 27 July 2026 |
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