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Paper · arXiv

Pretraining EHR Foundation Models with Patient-Aware Sampling

Autoregressive foundation models for electronic health records (EHRs) typically inherit pretraining methods from language modeling, where patient trajectories are concatenated into a single token stream and windows are sampled from that stream. In EHR data, this choice is consequential: windows may mix multiple patients, and patients with longer records contribute more optimization updates, potentially introducing bias. We propose Patient Sampling, a pretraining sequence-construction method that allows us to control how training signal is distributed across patients. We compare this method to the standard approach, which we refer to as Global Stream. We show that stochastic Patient Sampli...

AuthorsJoshua Placidi, Yuxuan Liu, Jinpei Han et al.
Primary categorycs.LG
Published24 July 2026
Last updated at source24 July 2026
cs.LG
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