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Paper · arXiv

AutoSynthesis: An agentic system for automated meta-analysis

Evidence synthesis is crucial for turning primary research into reliable knowledge for science, medicine, education, and policy. Yet, quantitative evidence synthesis remains largely manual and difficult to scale. Here, we introduce AutoSynthesis, an end-to-end multi-agent system for automated meta-analysis. Given a research question in natural language, AutoSynthesis formulates a search strategy, retrieves scientific literature, screens candidate studies, assesses full-text eligibility, extracts quantitative statistics, computes standardized effect sizes, and finally performs random-effects meta-analysis. AutoSynthesis further supports heterogeneity analysis to examine how effect sizes va...

AuthorsMoein Taherinezhad, Sebastian Maier, Gerardo Vitagliano et al.
Primary categorycs.AI
Published16 July 2026
Last updated at source16 July 2026
cs.AI
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