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Paper · arXiv

CRISP: Constrained Refinement via Iterative Squeezing Process for Robust Medical Image Segmentation under Domain Shift

Distribution shift in medical imaging remains a central bottleneck for the clinical translation of medical AI. Failure to address it can lead to severe performance degradation in unseen environments and exacerbate health inequities. Existing methods for domain adaptation are inherently limited by exhausting predefined possibilities through simulated shifts or pseudo-supervision. Such strategies struggle in the open-ended and unpredictable real world, where distribution shifts are effectively infinite. To address this challenge, we adopt the "Rank Stability of Positive Regions" as a working assumption under distribution shift, and use it to derive robust spatial hints for source-only segme...

AuthorsYizhou Fang, Pujin Cheng, Yixiang Liu et al.
Primary categorycs.CV
Published16 July 2026
Last updated at source16 July 2026
cs.CV
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