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Paper · arXiv

Diffusion MRI preprocessing affects ADC estimation and automatic PI-RADS v2.1 classification in bi-parametric prostate MRI

Diffusion-weighted imaging (DWI) is acquired as part of bi-parametric prostate MRI, but suffers from artifacts that degrade downstream quantitative and diagnostic performance. While DWI preprocessing is standard in brain imaging, its adoption in prostate imaging remains limited and lacks standardized pipelines. This study investigated the effect of different DWI preprocessing strategies on apparent diffusion coefficient (ADC) estimation and automatic Prostate Imaging Reporting and Data System (PI-RADS) classification. 268 cases were derived from the fastMRI prostate cohort by sequentially applying denoising, Gibbs-ringing correction, and diffeomorphic registration for susceptibility disto...

AuthorsChristos Kanakis, Mathias Perslev, Tim Schakel et al.
Primary categoryeess.IV
Published13 July 2026
Last updated at source13 July 2026
eess.IVcs.CV
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