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Paper · arXiv

Reliability-Aware CT-MRI Registration: A Quality Engineering Framework with Stability Analysis and Risk Classification

Multimodal CT-MRI registration is central to image-guided radiotherapy, surgical navigation, and diagnostic workflows, but most pipelines report only aggregate quality metrics without per-case reliability signals. We propose a reliability-aware framework that converts registration quality into Green/Yellow/Red risk categories using data-learned thresholds. CT images were registered to T1-weighted MRI using rigid and affine transformations on 90 paired slices from 18 patients across brain, abdominal, and neck anatomies. Reliability was assessed using Delta NMI, Delta SSIM, Dice overlap, registration stability, and inverse consistency error, combined into a single score R. Thresholds learne...

AuthorsNisreen Albzour
Primary categorycs.CV
Published1 July 2026
Last updated at source10 July 2026
cs.CV
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