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Paper · arXiv

Timesynth: A Temporal Fidelity Framework for Health Signal Digital Twins

Forecasting models for health-signal digital twins must preserve the oscillatory, frequency, phase, and state-transition dynamics of physiological signals, yet the pointwise metrics used to benchmark them cannot detect when these fundamental properties are lost. We show that this blind spot misranks models: across 11 architectures, models with comparable pointwise error diverge by up to 53° in phase accuracy, equivalent to roughly 123 ms for a 1.2 Hz cardiac rhythm and invisible to standard metrics. To enable development of models that escape such failures, we introduce TimeSynth, a controlled benchmarking framework with two reusable components: a physiologically grounded generator produc...

AuthorsMd Rakibul Haque, Shireen Elhabian, Warren Woodrich Pettine
Primary categorycs.LG
Published1 July 2026
Last updated at source1 July 2026
cs.LG
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