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Paper · arXiv

Agentic AI Enhances Physician Trust in Clinical Decision Making

Medical AI has shifted from reasoning to agentic AI, a new paradigm that autonomously invokes external tools during reasoning, rendering intermediate reasoning steps and tool outputs transparent to users. Although proven to outperform previous models, physician trust in agentic AI remains largely unexplored. To address this, three physicians evaluated 315 multimodal clinical cases quantifying both process-oriented cognitive trust and outcome-oriented behavioral reliance. Comparing agentic AI against non-agentic baselines, physicians exhibited significantly higher cognitive and behavioral trust for the agentic model (P < 0.001). Specifically, on treatment planning tasks, physicians trusted...

AuthorsZhiling Yan, Zhe Fang, David J King et al.
Primary categorycs.CY
Published16 June 2026
Last updated at source16 June 2026
cs.CYcs.AI
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