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Reduction of Probabilistic Chemical Reaction Networks

Programming adaptive behaviors at the cellular level is a long-standing goal that raises the question of how probabilistic computation can be implemented in biochemical systems. Chemical reaction networks (CRNs) provide such a substrate and have been shown to realize probabilistic models, including hidden Markov models and factor graphs, with dynamics reproducing Bayesian inference and belief propagation. However, encoding these algorithms typically requires prohibitively large reaction networks, and classical CRN reduction techniques do not directly apply. By recovering the factor graph structure encoded in Napp--Adams-compiled CRNs, we transport recent factor-graph reduction results to ...

AuthorsMauricio Montes, Gregoire Sergeant-Perthuis
Primary categorycs.LG
Published26 June 2026
Last updated at source26 June 2026
cs.LGmath.CT
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