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Paper · arXiv

Anatomy-Guided Residual Motion Diffusion for Controllable 4D Cardiac MRI Synthesis

Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions. To address this, we propose a 4D controllable generative framework for anatomically consistent data augmentation. A semi-supervised variational autoencoder learns a compact latent representation of anatomical volumes while jointly predicting aligned segmentation masks in a unified framework. Anatomical structure is then disentangled from temporal dynamics through a cascaded latent diffusion model (LDM). A static LDM generates subject-specific anatomy conditioned on clinical priors (diagnosis and volumes measures...

AuthorsYiheng Cao, Gustavo Andrade-Miranda, Jiatian Zhang et al.
Primary categorycs.CV
Published25 June 2026
Last updated at source25 June 2026
cs.CVcs.AI
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