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Paper · arXiv

Rethinking the Adaptation of Vision Foundation Models for Efficient Cell Segmentation

Cell segmentation is critical for computational pathology and biomedical discovery. While recent Vision Foundation Models (VFMs) have demonstrated remarkable universal feature representations, unlocking their full potential for cellular imaging is currently bottlenecked by resource-intensive adaptation paradigms. Existing methods typically rely on fine-tuning heavy visual encoders, leading to extensive computational overhead and a dependency on large-scale annotations. To address this, we propose the EffiCell-Seg framework for highly efficient cell segmentation without re-training the visual encoder. Our core insight is that pretrained VFMs intrinsically encode complementary structural pr...

AuthorsQing Xu, Xiangjian He, Wenting Duan et al.
Primary categorycs.CV
Published20 June 2026
Last updated at source20 June 2026
cs.CVcs.AI
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