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Paper · arXiv

Edge-Aligned Beam Placement in Scanning Probe Tomography via Reconstruction-Free Sequential Design of Experiments

In X-ray scanning probe tomography, reconstruction quality generally improves with larger numbers of projections. However, additional projections increase experiment costs, acquisition time, and the radiation dose imparted to the sample. One mitigation to these trade-offs is to adopt a sequential design of experiments, in which each subsequent measurement is determined as a function of previously acquired data in order to maximize information gain. In scanning probe tomography, a widely used heuristic to maximize information is to align beams with the edges of the sample. A key challenge, however, is that the true sample is unknown, so identifying edge-aligned beams typically requires rec...

AuthorsSan Dinh, Zichao Wendy Di, Matt Menickelly
Primary categoryphysics.med-ph
Published19 June 2026
Last updated at source2 October 2026
physics.med-phcs.CV
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