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Paper · arXiv

BioInsight: Multi-Agent Orchestration for Interactive Biomedical Knowledge Discovery

Biomedical deep-research systems increasingly retrieve and synthesize scientific evidence, but their outputs typically collapse heterogeneous evidence into static text, making provenance difficult to inspect and reuse. We formulate evidence-centered biomedical knowledge discovery, where disease-associated protein signals are transformed into a structured evidence state connecting proteins, pathways, publications, interactions, claims, and uncertainty. We introduce BioInsight, a provenance-preserving multi-agent orchestration framework built around typed artifact contracts and an independent Search Agent that decouples evidence acquisition from downstream mechanistic reasoning, supporting ...

AuthorsJieyi Wang, Bingxuan Li, Nanyi Jiang et al.
Primary categorycs.AI
Published19 June 2026
Last updated at source2 August 2026
cs.AI
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