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Paper · arXiv

Performance Analysis and Optimization of 3D Generative Diffusion Models across GPU Architectures

Diffusion models have become essential for high-fidelity 3D MRI synthesis, yet their deployment remains constrained by substantial GPU resource demands arising from hundreds of U-Net evaluations per sample and a highly heterogeneous kernel behavior. This paper performs a comprehensive performance analysis of the state-of-the-art medical diffusion model, Med-DDPM, across three generations of NVIDIA architectures to study kernel-level runtime breakdowns, instruction-mix characteristics, memory system utilization, warp-level activities, and profiler priority-score estimates. We show that training is overwhelmingly dominated by cuDNN convolution and implicit-GEMM kernels, with inefficiencies ...

AuthorsJeeho Ryoo, Yongchan Jung, Muhammad Ali Khaliq et al.
Primary categorycs.LG
Published11 June 2026
Last updated at source11 June 2026
cs.LG
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