Poisson Flow of Cortical Folding in Juvenile Myoclonic Epilepsy
Cortical folding reflects coordinated neurodevelopmental processes and is increasingly recognized as a sensitive marker of neurological disease. However, most existing analyses rely on indirect scalar summaries that do not explicitly model folding geometry itself. In juvenile myoclonic epilepsy (JME), a common genetic epilepsy, cortical abnormalities are often subtle, spatially distributed, and difficult to detect using conventional morphometric measures. We introduce a Poisson-equation--based framework that models cortical folding as a geometry-driven flow derived from mean curvature on the cortical manifold. By treating folding patterns as a stationary source--sink structure, the propos...
| Authors | Moo K. Chung, Luigi Maccotta, Aaron Struck |
|---|---|
| Primary category | cs.CV |
| Published | 7 June 2026 |
| Last updated at source | 2 September 2026 |
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