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Paper · arXiv

NeuroAlign: Hierarchical Multimodal Fusion of Dynamic and Structural Neuroimaging for MCI Analysis

Multimodal neuroimaging fusion of functional MRI (fMRI) and diffusion tensor imaging (DTI) provides complementary information for cognitive impairment analysis, but remains challenged by heterogeneous feature spaces and misaligned representations. We propose \textit{NeuroAlign}, a hierarchical framework for structured multimodal fusion. It introduces (1) \textit{Dual-Modal Hierarchical Alignment} (DMHA), which models multi-scale dynamic connectivity and aligns dynamic-static and functional-structural embeddings; and (2) \textit{Dual-Domain Hierarchical Interaction} (DDHI), which enables fine-grained modulation and global interaction between connectivity- and region-level features. To supp...

AuthorsXiongri Shen, Zhenxi Song, Jiaqi wang et al.
Primary categorycs.CV
Published31 May 2026
Last updated at source31 May 2026
cs.CVcs.AI
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