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Paper · arXiv

EpiEvolve: Self-Evolving Agents for Streaming Pandemic Forecasting under Regime Shifts

Epidemic LLM forecasters are usually trained and evaluated as static supervised models, whereas operational pandemic forecasting is a streaming process in which labels arrive after predictions and disease regimes shift over time. We study this mismatch in weekly COVID-19 hospitalization trend forecasting across five variant regimes. We introduce EpiEvolve, a self-evolving agent that wraps an LLM forecaster trained on the warm-start period and keeps its weights fixed during streaming. EpiEvolve adapts by storing forecast outcomes in a hierarchical episodic memory, reflecting on delayed labels, retrieving cases relevant to the current regime, and distilling recurring errors into strategic r...

AuthorsYiming Lu, Sihang Zeng, Zhengxu Tang et al.
Primary categorycs.AI
Published3 June 2026
Last updated at source3 June 2026
cs.AIcs.CL
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