A Pathology Foundation Model for Gastric Cancer with Real-World Validation
Gastric cancer remains a major cause of cancer mortality, yet its histological and molecular heterogeneity complicates diagnosis and risk stratification. General-purpose pathology foundation models (PFMs) often plateau on fine-grained endpoints central to gastric cancer care, and few have undergone rigorous prospective validation or clinical reader studies. We present GRACE, a Gastric-specific foundation model for Real-world Assessment and Clinical dEcision support. GRACE was developed from multicenter gastric pathology datasets totaling 48,364 primarily HE-stained whole-slide images from 37,493 patients. When evaluated on 28 clinically relevant tasks, GRACE consistently outperformed repr...
| Authors | Ling Liang, Jiabo Ma, Zhengyu Zhang et al. |
|---|---|
| Primary category | cs.CV |
| Published | 3 June 2026 |
| Last updated at source | 3 June 2026 |
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