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Paper · arXiv

Entropy Minimization without Model Collapse: Mitigating Prediction Bias in Medical Imaging

Entropy minimization (EM) is the dominant objective for test-time adaptation, yet its failure mode, model collapse, remains poorly understood. In this work, we show that distribution shifts can cause feature clusters corresponding to distinct classes in the model's representation space to merge, while the decision boundary remains fixed. This induces a systematic skew in the predicted class distribution, referred to as prediction bias. Prediction bias refers to a shift in the predicted class distribution, with some classes overrepresented and others suppressed. We show that entropy minimization amplifies this prediction bias by tightening the existing clusters, reinforcing the incorrect g...

AuthorsTim Nielen, Sameer Ambekar, Johannes Kiechle et al.
Primary categorycs.LG
Published1 June 2026
Last updated at source1 June 2026
cs.LGcs.CV
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