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Paper · arXiv

Prospective evaluation of multimodal respiratory failure prediction: Do chest X-rays improve performance beyond EHR signals?

Early prediction of respiratory failure is critical for timely clinical intervention in intensive care units. Existing electronic health record (EHR)-based models can continuously monitor physiologic deterioration, but they may not fully capture pulmonary pathophysiology reflected in chest radiographs (CXRs). In this study, we ask whether CXR information improves prospective prediction of invasive mechanical ventilation beyond EHR signals alone. We develop a gated multimodal framework that integrates structured EHR time-series data with CXR foundation-model representations. The gating module adaptively controls the contribution of imaging features based on patient-specific clinical contex...

AuthorsXiaolei Lu, Shamim Nemati
Primary categoryeess.IV
Published25 May 2026
Last updated at source27 May 2026
eess.IVcs.AIcs.LG
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