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Paper · arXiv

Uncertainty Reasoning with Large Language Models for Explainable Disease Diagnosis

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the verifiability and interpretability essential for trustworthy medical AI. We propose a neuro-symbolic reasoning framework that aligns LLMs with formal logic to enable explainable and formally verifiable medical diagnosis. Patient descriptions and clinical guidelines are embedded into a neural knowledge base, where LLMs extract structured medical entities, temporal relations, and fuzzy symptom patterns, which are decoded into a symbolic knowledge base expressed i...

AuthorsXiaoyang Fan, Yufan Cai, Zhe Hou et al.
Primary categorycs.AI
Published25 May 2026
Last updated at source25 May 2026
cs.AI
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