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Distance-Aware Joint Spatio-Temporal Graph Contrastive Learning for Major Depressive Disorder Diagnosis

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures time-varying interactions among brain regions and provides rich spatio-temporal information, yet current DFC-based methods face three limitations: sliding-window Pearson correlation yields noisy estimates sensitive to window length and motion artifacts; correlation-derived node features do not fully exploit frequency-domain properties of blood-oxygen-level-dependent (BOLD) signals; and most spatio-temporal graph models handle spatial structure and temporal dynamic...

AuthorsMuhammad Asif Hasan, Yanming Zhu, Xuefei Yin et al.
Primary categorycs.CV
Published22 May 2026
Last updated at source22 May 2026
cs.CV
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