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Paper · arXiv

MedExpMem: Adapting Experience Memory for Differential Diagnosis

Experienced physicians develop diagnostic expertise through clinical practice, acquiring not only disease knowledge but also the ability to differentiate confusable conditions. Current medical vision-language models (VLMs) lack this capability -- their parameters encode static knowledge that does not evolve across diagnostic encounters. We propose MedExpMem, an experience memory framework enabling VLM-based diagnostic agents to accumulate differential diagnosis expertise. Unlike retrieval-augmented generation, which retrieves encyclopedic disease descriptions, MedExpMem memorizes discriminative experience derived from the agent's own diagnostic failures and organizes them as pairwise diff...

AuthorsQianhan Feng, Zhongzhen Huang, Yakun Zhu et al.
Primary categorycs.LG
Published20 May 2026
Last updated at source20 May 2026
cs.LGcs.AIcs.CV
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