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Paper · arXiv

Benchmarking Machine Learning Architectures for Antimicrobial Stewardship in Pediatric ICUs

Antimicrobial stewardship (AMS) is critical in pediatric intensive care units (PICUs), where diagnostic uncertainty often drives broad-spectrum antibiotic use, increasing antimicrobial resistance and potential long-term harms. Machine learning offers a promising approach for identifying patient-level opportunities for stewardship interventions from electronic health record data, yet prior work has focused largely on adult populations and static tabular representations. We present a systematic benchmarking study of AMS intervention prediction in the PICU across the public Paediatric Intensive Care database a private cohort from the University Children's Hospital Zurich, Switzerland. We def...

AuthorsNiklas Raehse, Luregn J. Schlapbach, Daphné Chopard
Primary categorycs.LG
Published21 May 2026
Last updated at source15 September 2026
cs.LG
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