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Paper · arXiv

Adaptive Experimentation for Censored Survival Outcomes

Adaptive experimentation enables efficient estimation of causal effects, but existing methods are not designed for survival data with censoring, where event times are only partially observed (e.g., overall survival in cancer trials but with dropout). In this paper, we develop a novel framework for adaptive experimentation to estimate causal effects under right censoring. For this, we derive the semiparametric efficiency bound for the average survival effect curve as a function of the treatment allocation policy and thereby obtain a closed-form efficiency-optimal allocation policy. The policy generalizes classical Neyman allocation to survival settings by prioritizing patient strata where ...

AuthorsYuxin Wang, Dennis Frauen, Jonas Schweisthal et al.
Primary categorycs.LG
Published18 May 2026
Last updated at source18 May 2026
cs.LGstat.ML
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