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Paper · arXiv

Medical Context Distorts Decisions in Clinical Vision Language Models

Vision-language models (VLMs) are increasingly proposed for clinical decision support, yet their reliability in real-world scenarios that require integrating both visual and textual context from medical records remains poorly characterized. This paper identifies three failure modes: (1) modality over-reliance on text over images, (2) spurious reliance on irrelevant clinical history, and (3) prompt sensitivity across semantically equivalent inputs. We evaluate a diverse set of general-domain and medically-tuned open and closed VLMs on chest x-ray tasks using MIMIC-CXR. By systematically manipulating image-text alignment, clinical history, and prompt formulations, we found that VLM decision...

AuthorsDavid Restrepo, Ira Ktena, Maria Vakalopoulou et al.
Primary categorycs.CV
Published17 May 2026
Last updated at source17 May 2026
cs.CVcs.CL
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