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Paper · arXiv

Adversarial Fragility and Language Vulnerability in Clinical AI: A Systematic Audit of Diagnostic Collapse Under Imperceptible Perturbations and Cross-Lingual Drift in Low-Resource Healthcare Settings

Current clinical artificial intelligence (AI) systems are evaluated almost exclusively on clean, standardised, English-language inputs, conditions that do not reflect the realities of healthcare delivery in low-resource settings. This study presents the first systematic dual audit of two orthogonal safety vulnerabilities in clinical AI: adversarial image fragility and cross-lingual diagnostic drift. Using DenseNet121, the architecture underlying CheXNet, fine-tuned on the COVID-QU-Ex chest X-ray dataset (85,318 images; COVID-19, Non-COVID Pneumonia, Normal), we demonstrate that diagnostic accuracy collapses from 89.3% to 62.0% under a Fast Gradient Method (FGM) perturbation of epsilon=0.0...

AuthorsAnthonio Oladimeji Gabriel, Ahmad Rufai Yusuf
Primary categorycs.CY
Published16 May 2026
Last updated at source16 May 2026
cs.CYcs.AIcs.LG
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