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Paper · arXiv

AIM-DDI: A Model-Agnostic Multimodal Integration Module for Drug-Drug Interaction Prediction

Drug-drug interaction (DDI) prediction is a critical task in computational biomedicine, as adverse interactions between co-administered drugs can cause severe side effects and clinical risks. A key challenge is unseen-drug generalization, where interactions must be predicted for drugs not observed during training. Although multimodal DDI models exploit diverse drug-related information, their fusion mechanisms are often tied to specific prediction architectures, limiting their reuse across models. To address this, we propose AIM-DDI, an architecture-independent multimodal integration module that represents heterogeneous modality information as tokens in a shared latent space. By modeling d...

AuthorsYerin Park, Sangseon Lee
Primary categorycs.LG
Published14 May 2026
Last updated at source14 May 2026
cs.LGcs.AI
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